THAOS for Investigators
Welcome to the Investigator Portal of THAOS.net. The Investigator Portal is intended to keep you up to date with THAOS activity, publications and new data.
THAOS Scientific Board Meeting
The THAOS Scientific Board met on 16-17 May 2015 in Madrid, Spain, during the THAOS Investigator Meeting. The board focused their discussion on three key areas:
- The status of enrollment and data collection in THAOS
- Research questions and new ideas for advancing THAOS
- The latest understanding of disease progression based on THAOS
A full review of the meeting is available in the July Newsletter.
THAOS Investigator Meeting 2015
The following slides were presented to the Investigator Meeting in Madrid in May 2015.
- Non-invasive diagnosis and investigation of TTR amyloidosis – Claudio Rapezzi
- THAOS data updates - renal function – Stephen Gottlieb
- Myocardial contraction fraction. Ideas for analysis – Eric Steidly
- THAOS data updates: Natural History of ATTR - Michelle Turner and Teresa Coelho
Information on safety reporting
All events and serious adverse events (SAEs) for all subjects should be entered into the adverse events page in THAOS. All SAEs for patients being treated with tafamidis should be reported to Pfizer using the SAE reporting form and faxing to Pfizer within the required reporting times, according to the Pfizer SAE reporting guidelines.
SAE reporting forms and instructions are available through Firecrest
This video demonstrates how to undertake and record in THAOS sensory examinations that assess loss of nerve function and disease progression.
How to detect amyloid by aspiration of subcutaneous abdominal fat
A video showing how to detect amyloid by aspiration of subcutaneous abdominal fat, produced in association with the Groningen Unit for Amyloidosis Research & Development (GUARD) (www.amyloid.nl), is available to view here.
Natália Ferreira - Ophthalmologic signs and symptoms of TTR amyloidosis
This video describes the key ophthalmologic signs and symptoms of TTR amyloidosis